Bone Cement
History
The story of modern cements began with Otto Röhm’s invention in the early 20th century of polymethyl methacrylate (PMMA), a solid material with good biocompatibility.
In the 1960s Sir John Charnley began using bone cement on numerous patients for the fixation of both the femur and acetabulum. Before the end of the decade, Buchholz came up with the idea of adding an antibiotic to the cement to decrease the incidence of infection.
The evolution of bone cement
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1902 1936 1939 1940 1943 1949 1955 1959 1970 ~1990 2000 |
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First synthesis of PMMA by O. Röhm First industrial production of PMMA Animal studies on skull defects Human studies on skull defects Polymerisation of PMMA becomes possible at room temperature Judet brothers developed hip implant with PMMA Filling of spinal defects (Idelberger) Sir John Charnley uses PMMA cement in hip replacement; femur and acetabulum implant is fixed by bone cement Buchholz used PMMA bone cement with gentamicin; E. Merck starts marketing bone cement. Focus on cementing technique in trade publications 1 million implants fixated with bone cement worldwide |
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