Clindamycin belongs to the group of lincosamide antibiotics. It is additionally active against some anaerobic germs, such as peptostreptococci, anaerobic germs. This activity makes it a suitable antibiotic in combination with gentamicin, covering most of the germs typically occuring in periprosthetic infection.
Gentamicin and clindamycin is a combination known to have a bacterical effect on more than 90% of the bacteria common to infected arthroplasty cases.8

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